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Posted: 17 October 2026
5 Minute ReadSKIN1004 Lab In Nature: Where Powerful Actives Meet Soothing Centella
Powerful actives meet soothing Centella! Discover four new additions to SKIN1004's Lab In Nature collection, featuring Azelaic Acid, PDRN, Azulene and NAD. Find out what makes each formula special and which one is right for your skin.
If you're into skincare, you've probably noticed ingredient lists getting a little more interesting. Azelaic acid, PDRN, NAD: there's always something new to discover. But with so many powerful actives out there, finding the right one isn't always easy, especially if your skin tends to be sensitive.
So, what if you could explore these ingredients without leaving soothing skincare behind?
Meet SKIN1004 Lab In Nature, a collection that brings targeted actives together with the calming care of Madagascar centella.
SKIN1004's original philosophy, The Untouched Nature, celebrates purity. Lab In Nature explores possibility: taking nature-inspired skincare further through research and thoughtful formulation. It's the same SKIN1004 you know and love, with new possibilities for your skin.
New to Lab In Nature: Four Formulas Worth Knowing
Lab In Nature started with SKIN1004's Boosting Shot Ampoules. Now it welcomes four new formulas, each built around one ingredient you've probably seen trending: Azelaic Acid, PDRN, Azulene and NAD.
a higher percentage doesn't always mean a better product. it's how the ingredients work together that counts.
That's the idea behind Where Nature Meets Precision. Each formula pairs a high-purity active with supporting ingredients for one skin concern, so you get targeted care without leaving comfort behind.
Swipe to see all 4 ›
Azelaic Acid
SKIN1004
SKIN1004
Azelaic Acid 10 Ampoule
Best for: blemish-prone, oily and combination skin
Tackles: blemishes, visible marks, uneven tone
Bonus: centella and panthenol to soothe and hydrate
Good to know
£22.00
Shop now ›
- What it is: a naturally occurring acid that helps improve the look of blemishes, lingering marks and uneven tone.
- Triple Azelaic Formula (11.5%): 10% azelaic acid plus two gentler derivatives, potassium azeloyl diglycinate and azelamide MEA.
- Encapsulated: wrapped for better stability and a more comfortable feel on skin.
- Texture: watery and non-comedogenic, with no tacky finish.
PDRN
SKIN1004
SKIN1004
PDRN 1.5 Cream
Best for: dry, dehydrated and stressed skin
Tackles: dryness, dehydration, a stressed barrier
Bonus: 8GF Complex and zinc hyaluronate (HA-Zn)
Good to know
£18.00
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- What it is: short for polydeoxyribonucleotide, a chain of DNA fragments known for skin-conditioning care.
- Clinic vs cream: injectable PDRN is a professional treatment; topical PDRN is for daily hydration and barrier support.
- Vegan BIOME PDRN: 99% pure and made through fermentation, an animal-free alternative to salmon-derived PDRN.
- Texture: rich care in a lightweight cream, without the thick, sticky feel.
Azulene
SKIN1004
SKIN1004
Azulene Peptide 5 Soothing Cream
Best for: sensitive, redness-prone and heat-stressed skin
Tackles: redness, heat, discomfort
Bonus: 5-Peptide Firming Complex for firmer-looking skin
Good to know
£18.00
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- What it is: a soothing compound derived from chamomile, famous for its blue colour.
- Why heat matters: beyond UV, heat can leave skin looking red and feeling uncomfortable.
- Dual Azulene Complex: 500ppm of 99% pure azulene plus two azulene derivatives, with patented cooling technology.
- Natural colour shifts: its plant-derived ingredients can change colour with storage. It's still safe to use; keep it at room temperature, away from sunlight.
NAD
SKIN1004
SKIN1004
NAD 0.1 Cream
Best for: early signs of ageing
Tackles: fine lines, loss of firmness
Bonus: adenosine for firmer-looking skin
Good to know
£17.00
Get notified ›
- What it is: nicotinamide adenine dinucleotide, a coenzyme found in every cell that helps turn nutrients into energy. Our levels naturally dip with age.
- Why it's trending: NAD is an emerging ingredient in anti-ageing skincare, though its topical benefits are still being explored.
- High-purity NAD 0.1%: 1,000ppm of 99% pure NAD, carried by elastic liposomes.
- 5 antioxidants: resveratrol, CoQ10, astaxanthin, and vitamins C and E.
So, Which One Does Your Skin Actually Need?
The good news? You don't need every active in your routine. Start with what your skin needs most.
If your concern isBlemishes, visible marks and uneven toneAzelaic Acid 10 Ampoule ›
If your concern isDryness, dehydration and barrier carePDRN 1.5 Cream ›
If your concern isRedness, irritation and overheated skinAzulene Peptide 5 Soothing Cream ›
If your concern isFine lines and loss of firmnessNAD 0.1 Cream ›
Got sensitive skin? Lab In Nature pairs each active with supporting ingredients chosen with comfort in mind. Everyone's skin responds differently, though, so introduce new products gradually and patch test first.
Explore the SKIN1004 Lab In Nature Collection
Swipe to see all 7 ›
Discover SKIN1004 Lab In Nature and find the formula that fits your skin's needs.
Shop All SKIN1004SKIN1004 Lab In Nature: Frequently Asked Questions
What is SKIN1004 Lab In Nature?
Lab In Nature is a SKIN1004 collection that pairs targeted active ingredients with the calming care of Madagascar centella. Where SKIN1004's original philosophy, The Untouched Nature, celebrates purity, Lab In Nature explores possibility: taking nature-inspired skincare further through research and thoughtful formulation.
Which Lab In Nature product is right for my skin?
Start with your main concern. For blemishes, visible marks and uneven tone, choose the Azelaic Acid 10 Ampoule. For dryness, dehydration and barrier care, choose the PDRN 1.5 Cream. For redness and overheated skin, choose the Azulene Peptide 5 Soothing Cream. For fine lines and loss of firmness, choose the NAD 0.1 Cream.
Is topical PDRN the same as PDRN injections?
No. Injectable PDRN is delivered into the skin by a professional in a clinic. Topical PDRN, like the PDRN in the PDRN 1.5 Cream, is applied to the surface of the skin as part of an everyday routine, with a focus on hydration and comfort rather than injectable-level results.
Is the PDRN in the PDRN 1.5 Cream vegan?
Yes. The PDRN 1.5 Cream uses 1.5% vegan BIOME PDRN, produced through fermentation rather than sourced from salmon.
What is the 11.5% Triple Azelaic Formula?
It is the combined total of three azelaic ingredients in the Azelaic Acid 10 Ampoule: 10% azelaic acid, 1% potassium azeloyl diglycinate and 0.5% azelamide MEA. The two derivatives are gentler forms of azelaic acid, and the azelaic acid itself is encapsulated to improve stability and comfort.
Is Lab In Nature suitable for sensitive skin?
Each formula pairs its active with supporting ingredients chosen with skin comfort in mind, including Madagascar centella. Everyone's skin responds differently, though, so introduce one new product at a time and patch test first.
About the publisher
Team Skin Cupid
Skin Cupid is a specialist in Korean and Asian beauty, online and at our flagship store in central London. We curate, test and demystify Asian skincare for UK skin, working directly with brand teams to bring you guidance you can trust.